What’s Sodium hyaluronate?
Sodium hyaluronate is the sodium salt of Hyaluronic Acid, sodium Hyaluronate is a polymer of disaccharides, which are composed of D-glucuronic acid and D-N-acetylglucosamine, linked via alternating beta-1,4 and beta-1,3 glycosidic bonds. It was first found by Karl Meyer in 1934 and named hyaluronan.
Where is Sodium Hyaluronate Found?
Sodium Hyaluronate distributes widely in human body, such as in connective, epithelial, and neural tissues. Sodium Hyaluronate can be found in synovial fluid, hyaloids of eyes, skin and umbilical cords of mammals.
Why is Sodium Hyaluronate Important?
Sodium Hyaluronate plays an important role in human biologic activity. With the increase of age, content of Sodium Hyaluronate in the body will decrease. The decrease of Sodium Hyaluronate content in human body will weaken the water retaining ability of the skin, make the skin look coarse and wrinkle; lead to arthritis, arteriosclerosis, plus disorder and brain atrophy, and finally premature senility.
Sodium Hyaluronate is a safe agent for plastic surgery and many medical applications, as Sodium Hyaluronate is already found in human body, no need to worry about the immune responses or reject by our body.
Properties of Sodium Hyaluronate
The Sodium Hyaluronate is a kind of white powder. It possesses many hydroxyl groups and shows a strong water retentivity. Its high-molecular weight nature generates a large viscosity when it is dissolved in water.
Commercial Preparation of Sodium Hyaluronate
It can be obtained by extracting from cockscomb or through microorganism fermentation. The product in our company is all fermented products. The stain is Streptococcus equi subsp. Zooepidemicus, one of the naturally occurring lactic bacteria, and it does not involve any recombinant process. Sodium hyaluronate can be defined for different grade as
Food Grade Sodium hyaluronate
Cosmetics Grade Sodium hyaluronate
Medical Grade Sodium hyaluronate
Injection Grade Sodium hyaluronate
They require different purification process and used for different applications.
Production Flow Chart of Sodium Hyaluronate
Application of Sodium Hyaluronate:
With the special properties, Sodium Hyaluronate is widely used in food industry, cosmetics products, ophthalmology application, plastic surgery industry and other medical applications.
Application of Food Grade Sodium Hyaluronate
An important nutritional ingredient, used in food or health product as a dietary supplement to supply Sodium Hyaluronate in the body.
Application of Cosmetics Grade Sodium Hyaluronate
Skin care products: cream, emulsion, essence, lotion, gel, facial mask, etc.
Beauty products: lipstick, eye shadow, foundation, etc.
Cleansing products: facial cleanser, body wash, etc.
Hair products: shampoo, hair conditioner, styling gel, hair restorer, etc.
Application of Pharmaceutical Grade (Medical Grade) Sodium Hyaluronate
Produce oral preparations or parenteral preparations. It can be used in eye drops, drug carrier, contact lens solutions, topical preparations for wound or burn healing, medical lubricants, etc. but not including intra-articular and intra-ocular preparations.
Application of Injection Grade Sodium Hyaluronate
Produce intra-articular and intra-ocular preparations, such as Ophthalmic Viscosurgical Device, intra-articular injections, intradermal injections for aesthetic correction, anti-adhesive products, etc.